Education

2002-2007 Innovation Academy for Precision Measurement Science and Technology, CAS，Ph.D

1998-2002 Wuhan University，Physics，Bachelor

Academic Experience

2023-now  Changping Lab

2015-2022 Wuhan National laboratory for Optoelectronics, Huazhong University of Science and Technology, Full Professor

2008-2015 Purdue Univeristy, Department of Physics, Chemistry and BME, Postdoctoral researcher

2007-2008 Innovation Academy for Precision Measurement Science and Technology, CAS, Assistant Professor

Overview of Academic Research

As a highly interdisciplinary research team, our graduate students came from the Department of Physics, Chemistry, Biology, EE, ECE, Optoelectronics and many other schools. We work passionately for the goal to explore and innovate molecular imaging techniques in basic life science and clinical applications. By pursuing quantitative and precision measurements in biology as it is in physics, our enthusiasm focuses on optical super-resolution imaging, deep tissue imaging, tissue tomography, smart genetic Raman tags to overcome the current instrumental limitations and answer important biological questions through our new ideas and even sudden inspiration after years of pondering. These new and robust methods will substantially extend our capabilities in observation of the nano-architectures of single cells and help us access the genetic trees of proteins and metabolites via molecular Raman imaging. Life is based on chemicals and unthinkable high-efficient chemical reactions. We set our mind on contributing our faint lives and energy to developing magic optical imaging tools to help us look into the life more closely. Hopefully, it can be the most disruptive one in the future.

Representative Research Achievements 

1.  Y. Bi#, C. Yang#, Y. Chen, S. Yan, G. Yang, Y. Wu, G. Zhang* and P. Wang*. Near-resonance enhanced label-free stimulated Raman scattering microscopy with spatial resolution near 130 nm. Light: science & applications 7, 81 (2018) (IF: 20.26)

2.  B. Huang#, S. Yan#, L. Xiao, R. Ji, L. Yang, A. J. Miao* and P. Wang*. Label-Free Imaging of Nanoparticle Uptake Competition in Single Cells by Hyperspectral Stimulated Raman Scattering. Small 14, (2018) (IF: 15.15)

3.  H. Li, Y. Cheng, H. Tang, Y. Bi, Y. Chen, G. Yang, S. Guo, S. Tian, J. Liao, X. Lv, S. Zeng, M. Zhu, C. Xu, J. Cheng* and P. Wang*. Imaging Chemical Kinetics of Radical Polymerization with an Ultrafast Raman Microscope. Advanced Science 7, 1903644 (2020) (IF: 17.52)

4.  Y. Bi#, C. Yang#, L. Tong#, et al., W. Bao*, L. Ye* and P. Wang*. Far-field transient absorption nanoscopy with sub-50 nm optical super-resolution. Optica 10, 1402 (2020) (IF: 10.64)

5.  S. Tian, et al, F. Meng*, J. Lauher*, P. Wang* and Liang Luo*. Polydiacetylene-based Ultrastrong Bioorthogonal Raman Probes for Targeted Live-cell Raman Imaging. Nature Communications 11, 81 (2020) (IF: 17.69)

6.  C. Yang#, Y. Bi#, E. Cai, Y. Chen, S. Huang, Z. Zhang, and P. Wang*. Pulse-Sheet Chemical Tomography by Counterpropagating Stimulated Raman Scattering. Optica 8, 3 (2021) (IF: 10.64)

7.  G. Yang#, C. Yang#, et al, Y. Wang*, J. Xia* and P. Wang*. Direct Imaging of Integrated Circuits in CPU with 60 nm Super-Resolution Optical Microscope. Nano Letters 21, 3887 (2021) (IF: 12.26)

8.  W. Zhu#, E. Cai#, H. Li#, P. Wang*, A. Shen*, J. Popp* and J. Hu*. Precise Encoding of Triple-bond Raman Scattering of Single Polymer Nanoparticles for Multiplexed Imaging Application. Angew. Chem. Int. Ed. 60, 21846-21852 (2021) (IF: 16.82)

9.  Y. Ma#, H. Li#, Z. Gong, S. Yang, P. Wang* and C. Tang*. Nucleobase Clustering Contributes to the Formation and Hollowing of Repeat-Expansion RNA Condensate. J. Am. Chem. Soc. 11, 4716-4720 (2022) (IF: 16.38)

10. J. G. Davis, K. P. Gierszal, P. Wang, D. Ben-Amotz*. Water structural transformation at molecular hydrophobic interfaces. Nature 491, 582-585 (2012) (IF: 49.962)